SS400 - Statistical Analysis of Microarray Data

Description:

This course will provide an overview of statistical issues that arise in the design and analysis of microarray studies. The course will begin with a discussion of the various sources of variability inherent in microarray experiments, methods of evaluating data quality, and data normalization techniques. Focus will then shift to outlining the main types of scientific questions that investigators aim to answer from microarray experiments, accompanied by an in depth discussion of proper design and analysis strategies for addressing each of the specific types of questions. The second day will be a "hands-on" demonstration of BRB Array Tools. This microarray data analysis software package will be used to demonstrate and reinforce some of the concepts discussed in the first day. Students are welcome to bring their own data for in-class exercises.



Objectives:

Topics to be covered include:
  • Sources of variability in array experiments
  • Data quality assessment
  • Data normalization
  • Analysis and visualization methods
  • Clustering methods
  • Class prediction methods
  • Permutation tests
  • Multiple comparisons procedures
  • ANOVA models


Reasonable Accommodations

Individuals who need reasonable accommodation to participate in CIT Training courses should let CIT Training know at least 5 days prior to the class. For interpreting services, please request them from the ORS Interpreting Services by completing the form at Interpreting Services Form or calling (301) 402-8180 or TTY (301) 435-1908 at least 5 days before the start of the class.

Who should attend:

Priority will be given to those using NCI's Advanced Technology Center (ATC), FDA/CBER, and NIAID microarray prints. Others interested in advanced microarray analysis as space permits.

Instructor(s):

Dr. Lisa McShane, NCI ; Dr. Joanna Shih, NCI

Time Required:

4 Hours

Sections Available:

Add to CartDateTimeLocationSeats AvailableTuition
November 12 - November 1312:30 PM - 4:30 PMBuilding 12A - Room B51350



NOTE: Since there are no open sessions; we can waitlist you and contact you when a section opens up.